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Project partners

Politecnico di Milano


Lead: Prof. Pasquale Vena

POLIMI

Politecnico di Milano is a state scientific-technological university established in 1863 which trains engineers, architects and industrial designers.  Education is at Bachelor, Master’s, and PhD level. Currently more than 1,500 professors and researchers work at University and 47,170 students study in 7 different campuses. POLIMI is one of the leading Italian research centers characterized by the combination of theoretical bases of excellence and first-rate research infrastructures providing the possibility of wide variety of experimental research. POLIMI is organized in 12 Departments including all main areas of engineerng, architecture and industrial design.In 2015 POLIMI achieved the European “HR Excellence in Research” Logo, concerning the implementation of the principles of the European Charter for Researchers and of the Code of Conduct for the Recruitment of Researcher:  https://euraxess.ec.europa.eu/jobs/hrs4r.

Politecnico di Torino


Lead: Prof. Francesco Baino

POLITO

POLITO is among the top Engineering and Technology universities in the world, the 39th according to the QS University Rankings 2021 by broad Subject. In 2017 POLITO was the 1st one in the Graduate Employability Ranking. In November 2013 POLITO has been acknowledged by the EU Commission for its commitment towards the implementation of the EU Charter for Researchers and a Code of Conduct for the Recruitment of Researchers through the ‘HR Excellence in Research’ award. It has a yearly budget of about €300 million and over 37,000 students enrolled in academic courses (19% of them are international students). POLITO international education network features about 413 bilateral agreements and 120 double-degree agreements with EU and non-EU universities, active participation in university networks and the establishment of international campuses (e.g., Sino-Italian campus of Tongji University in Shanghai). POLITO has more than 50 permanent partnerships in research and education with industries for innovation, development or talents training.

Università del Piemonte Orientale


Lead: Prof. Lia Rimondini

UPO

Università del Piemonte Orientale is a public multi-campus university located in Regione Piemonte. The Department of Health Science (DiSS) belonging to UPO is one out of the 20 “Medical Sciences” Departments that have been awarded as a “Italian Department of Excellence 2018-2022” based on a competitive selection process carried out by the Italian Government. DiSS quickly moves new knowledge of basic science to biomedical science, aimed to create advanced diagnostic and therapeutic applications as well as new tools of investigation. The translation is the most up-to-date approach for training new doctors and biotechnologists, both undergraduates and postgraduates. This approach takes in some specific topics of medical-biological: surgery, dentistry, orthopedics, physiatry, pediatrics, dermatology and pathology.

University of Liege


Lead: Prof. Davide Ruffoni

ULG

The Department of Aerospace and Mechanical Engineering aims at developing advanced technologies and engineering solutions in the fields of aerospace engineering, biomechanics, energy conversion, and mechanical systems. A&M has achieved international recognition for the development of advanced numerical simulations at multiple length scales. The strong computational expertise is combined with innovative manufacturing and material characterization methods to develop new solutions and predictive models for a variety of applications ranging from aerospace to tissue engineering. These core competences match very well the scope of REBONE. Specifically, the multi-scale computational expertise will be exploited to develop models on the bone-scaffold system able to capture complex microstructures. The vast knowledge on modelling of complex materials is beneficial to build computational models on bone tissue, which is a challenging inhomogeneous and anisotropic polymer-ceramics composite. A&M staff amounts to more than 120 people, including 24 academics (3 of them has received ERC grants), 4 permanent researchers, more than 80 researchers (including PhD candidates), and 15 people in the administrative and technical staff.

Lithoz


Lead: Dr. Martin Schwentenwein

LTZ

Lithoz is a R&D driven SME which develops and distributes AM systems for ceramic materials on the basis of the patented Lithography-based Ceramic Manufacturing (LCM)–technology. This technology is capable of structuring a broad range of photopolymers, including ceramic filled resins. LTZ covers the whole process chain from the material development over the material processing to the development of the hard- and software, making them to a strong partner for R&D projects. LTZ is continuously developing their LCM process and is building up a unique know-how in this field through continuous innovation and development. LTZ currently employs 38 researchers working on the development of the machine, photopolymerizable resins, ceramics, software, and application technology.

Ludwig Boltzmann Institute of Osteology


Lead: Mag. Dr. Barbara Misof

LBI

The Ludwig Boltzmann Institute of Osteology (LBI) is the scientific core center within a multidisciplinary clinical network located at two large hospitals in Vienna (the Hanusch Hospital and the Trauma Centre Meidling) targeting diagnosis and treatment of bone and joint diseases. Its mission is to achieve the highest level of scientific excellence through basic and clinical research in osteology, as well as the training of young scientists and clinicians. The primary goal is the improvement of patient care. Towards this goal, the study of bone is undertaken at all hierarchical levels through a multidisciplinary approach by a worldwide unique combination of techniques. The aim is the elucidation of the mechanisms underlying the basic function of bone, and musculoskeletal diseases, leading to the discovery and development of effective strategies for diagnosis, prevention, and treatment. For example, ongoing research provides insights into the basis of bone fragility in osteoporosis and osteogenesis imperfecta. The gained knowledge provides benchmarks against which current therapies are evaluated, and provides the basis for the design of new, targeted ones. To achieve the stated goal, LBI basic scientists and clinicians in tandem with national and international collaborators as well as industry, are utilizing LBI expertise and available combination of analytical approaches to study bone at all hierarchical levels. The existing combination of instrumental capabilities allows analyses to be performed from a clinical, cell & molecular biology, physical chemical, and material science perspective.

University of Salzburg


Lead: Prof. Dr John W. C. Dunlop

PLUS

The Paris-Lodron University of Salzburg is a small university set in the heart of Europe, with a strong background in interdisciplinary research. The university currently has 4 main missions (Art in Context, Digital Life, Development and Sustainability, and Health and Mind). Of these the directions of “Health and Mind” and “Digital Life” have strong links to the goals of the action. Much is planned in the University especially in the context of collaborations between Digital Sciences (Computer Science, Mathematics) and the Biological and Physical Sciences in the direction of dealing with Big Data. This is especially important when looking at the complex 3D data sets produced in the analysis of tissues in bone-regeneration. The MorphoPhysics group in the Department of the Chemistry and Physics of Materials has a strong focus on the biophysics of tissue growth using a combination of advanced in-vitro 3D imaging capabilities and computational modelling. The group aims to explore the role of geometric principles on the kinetics of tissue growth as well as the spatial organization of the extracellular matrix. In addition, the group works on understanding the role of 3D tissue architecture on the functional properties of tissues supported using a combination of 3D printing, and mechanical modelling.

Faculty of Technology and Metallurgy, University of Belgrade


Lead: Prof. Bojana Obradovic

UOB

Faculty of Technology and Metallurgy, University of Belgrade, UOB, has a long-standing tradition in higher education and scientific research in chemical engineering, biotechnology, materials engineering, environmental engineering, and metallurgy, and offers bachelor, master, and doctoral studies in these fields. UOB has significant results in numerous national and international scientific projects and among variety of research fields, materials engineering is one of the strongest. Also, in the year 2000, Prof. B. Obradovic has initiated research in biomedical engineering. In 2004 the laboratory operated under her supervision, was renovated by the Ministry of Science of the Republic of Serbia as a potential centre of excellence for biomedical research in the country. Since then several national and international scientific projects focused on cell immobilization, interactions of cells and novel biomaterials, and development of novel bioreactors for skeletal tissue engineering, have been carried out. In REBONE project UOB will be the leader of WP4 and in charge of developing in vitro models for studies of cell- and tissue-biomaterial interactions. Also UOB will host secondments and provide training to DCs in the bioreactor set-up and utilization in cell and tissue cultures.

MedApp


Lead: Andrzej Skalski

MEDAPP

MedApp is a technology company operating in the field of digital healthcare combining the knowledge and experience of researchers, engineers, and clinical physicians. MedApp offers unique, new-generation medical data visualization solutions. The main product developed by MedApp is the CarnaLife Holo® – breakthrough technology for 3D holographic visualisation in mixed reality which supports the planning and performance of medical procedures. It has been used successfully during advanced cardiac/orthopedic/surgical/urological medical treatments. CarnaLife Holo application is dedicated to ultimate volumetric data visualization as holograms inside operation theatre using HoloLens 2 headset produced by Microsoft. Voice commands and hand gestures allows easy data interaction and great depth perception of 3-dimensional space. System supports all image data in standard DICOM format, including computed tomography, 3-dimensional rotational angiography, echocardiography and magnetic resonance images. Thanks to cooperation with the biggest medical devices producers, application allows real-time data streaming from selected devices like for instance Vivid E95, GE.

EU CORE Consulting


Lead: Dr. Irene Liverani

EUCORE

EU CORE is a private company providing project identification, design, management, accounting, evaluation and partnership services for public and private organizations across Europe. Building on a large experience of consultancy on fundraising and on EU projects’ implementation, EU CORE organises and holds, also remotely, a wide range of training courses on a variety of issues related to EU project design and management, focusing particularly on Horizon Europe, aimed at both researchers and administrative staff, most of them belonging to universities and research centres (in the last five years EU CORE has trained roughly 700-800 people per year in all aspects related to EU research programmes design and management, including IPR issues.

Cerhum


Lead: Dr. Gregory Nolens

CERHUM

Cerhum is a company providing 3D printing of bioceramic for medical applications. This company has developed MyBone, an advanced 3D bone graft. Cerhum uses this solution to manufacture patient specific bone graft, and also provide it to other companies as a legal contract manufacturing organization for different applications. Cerhum has developed a strong expertise on 3D printing from material development to final product. Cerhum works with product manufacturer, research centres, and medical staff to provide innovative solutions in life science. Cerhum is certified ISO 13485, meaning its process has reached a reference in quality for medical device production. Cerhum was created in 2016, and employs a team of 10 people.

Science on the Street


Lead: Dr. Saša Novak Krmpotič

SoS

The Science on the Street, institute for the promotion of science, is a non-profit organization in public interest. The team consists of researchers and science communicators. Since 2013, the team has been organizing public lectures on science and technology (>150), science slams, science-related round tables, workshops and various competitions. It supports science communication in research projects; provides science communication workshops and lectures; Role in the project: fostering communication activities, support in science communication plan; establishing social media accounts; science communication workshops.

Tampere University


Lead: Prof. Massera

TAU

The multidisciplinary, foundation-based Tampere University is Finland’s second-largest university with over 20 000 students and 330 professors. TAU conducts scientific research in technology, health and society and provides the highest education within these fields.
In 2021, the total income of TAU was 335 M€ of which 27 % was external R&I funding. TAU ranks fourth among all Finnish participants in Horizon Europe funding. TAU promotes sustainable development in community and in teaching, research, innovation and development, and societal interaction. The Equality and Non-Discrimination Policy 2021–2022 of TAU sets out the legal obligations and promotes equality and diversity policies in line with the University’s strategy. TAU has received the European Commission’s “HR Excellence in Research” award. The university researcher community and support services have long experience on EU funding. TAU has an EU support team dealing with financial and administrative issues.

Université Paris-Est Créteil


Lead: Prof. Nicolas Bochud

UPEC

The Multiscale Modeling and Simulation Laboratory (MSME) is a Joint Research Unit between Université Paris-Est Créteil (UPEC), Université Gustave Eiffel (UGE), and CNRS (UMR 8208). The research conducted at the laboratory focused on theoretical chemistry, mechanics, heat and material transfers, and biomechanics. The research activities of the BIOMECA team include the development of numerical and experimental approaches to characterize living tissues as well as investigate the mechanics of growth, remodeling and repair of living tissues at different hierarchical levels. The team dedicates a large part of its activities to producing scientific knowledge and methodologies related to the fundamental understanding of the processes characterizing living environments. Nevertheless, a growing part of its activities also consists in setting up finalized research in the clinical context via the creation of diagnostic aid devices and clinical translational protocols.

AUVA Trauma Centre Meidling


Lead: Dr. Mittermayr

AUVA

AUVA (Allgemeine Unfallversicherungsanstalt) is the social insurance for occupational risks. It operates a total of 6 trauma hospitals and is thus the largest organization for the treatment of accidents in Austria. The largest trauma hospital is the AUVA Trauma Center Vienna, Meidling with about 140,000 patients treated per year. Thus, AUVA has access to a large amount of patient data that can be used anonymously for the study proposal. In addition, there is a high level of clinical expertise to act in an advisory capacity for the study. Data will be provided in compliance with the applicable data protection regulations and in accordance with good clinical practice guidelines.